Treatment for beta-thalassemia varies depending on the severity of the disorder. People with beta-thalassemia major and intermedia should be monitored through regular hematological evaluations. During pregnancy, illness or infection, there is a higher chance of triggering or aggravating anemia in people with beta-thalassemia. Beta-thalassemia Minor People with Beta-thalassemia minor typically do not have symptoms other [...]

Beta-thalassemia is diagnosed using genetic testing and blood tests. Genetic testing DNA testing of the HBB gene can be used to diagnose beta-thalassemia. The beta-thalassemia DNA test detects the most common HBB genetic mutations known to cause beta-thalassemia. Prenatal testing may be considered if both parents are carriers of mutations known to cause beta-thalassemia. Blood [...]

The signs and symptoms of beta-thalassemia can vary in severity depending on the extent of HBB gene deficiencies. The severity of the disease is classified into three types in the order of decreasing severity: β-thalassemia Major, β-thalassemia Intermedia and β-thalassemia Minor. β-thalassemia Major People with β-thalassemia Major usually have no symptoms at birth, but signs [...]

Beta-thalassemia is caused by genetic mutations in the HBB gene which affect the production of β-globin. Insufficient β-globin decreases the amount of functional hemoglobin (HbA), thereby decreasing the amount of red blood cells for maturation. This can lead to anemia and other symptoms in people with beta-thalassemia. More than 300 mutations in the HBB gene [...]

Beta-thalassemia is an inherited blood disorder characterized by low levels of hemoglobin, leading to anemia and insufficient oxygen supply to the body. Common symptoms include jaundice, fatigue, organ damage, and delayed growth and development. Hemoglobin is an iron-containing protein in red blood cells that carries oxygen to the rest of the body. Normal hemoglobin (HbA) [...]